	EARLY Trial	UCSF School of Nursing
	Endothelial Assessment of Risk from Lipids in Youth	University of California, San Francisco

T O P I C S
EARLY Trial Team
Contact Information
Purpose of the Study
Study Design
Skin-Fold Measurement
Vascular Ultrasound
Who Can Participate?
What Are We Doing?
What Did We Find?
Body Mass Index
Cholesterol Facts
Heart Healthy Diet
Commonly Asked Questions
Participation Opportunities
A Note from Our Dietitian
Dietary Guidelines (.pdf, use reader)
Heart Healthy Lifestyle (.pdf, use reader)
Take a Quiz!
Comments from Participants
Web Site Links
Photo Gallery

EARLY Trial

This web site is for the "EARLY Trial" research study at UCSF School of Nursing. EARLY is an acronym that stands for:

Endothelial
Assessment of
Risk from
Lipids in
Youth

The main aim of this study is to find out if various supplements, along with following a NCEP Step II Diet (low cholesterol diet), will help to improve endothelial function, or ability of blood vessels to dilate, in children and adolescents who have high cholesterol.

Featured Page Topics

Cholesterol Facts: This section will give you the A-Z about cholesterol! Everything you need to know about the "Big C," from explaining what exactly cholesterol is, to why you need to worry about it now. It's time for you to get your cholesterol facts straight and be more informed about your heart health.
Heart Healthy Diet: A short introduction will help you to understand all about the first treatment program the participants go through. The National Cholesterol Education Program (NCEP) and the American Heart Association have developed a program for a low fat, low cholesterol diet, which is recommended if you are at risk for heart disease. A description of the NCEP Step II diet will be reviewed and links will be provided to give you more information.
Commonly Asked Questions: You probably have tons of questions about this research study. We're glad you are interested and want to learn more about the EARLY Trial. Here is a list of the top 10 most commonly asked questions. Please feel free to contact us with any other further questions; we would be happy to talk to you more!
Participation Opportunities: Learn more about how you can become a participant in the EARLY Trial. We have an exciting and innovative program set up for both kids and parents who want to take control of their heart health. An activity schedule is provided also with details about each visit and all the things that you can expect.
A Note from Our Dietitian: One of the biggest incentives to this study is that you will be able to work with a certified nutritionist. He or she will be able to give you and your family individualized information about every nutrition fact that you need to know. Here our dietitian says a few words about changing your diet and lifestyle habits to be heart healthy!
Take a Quiz!: We hope this website has provided you with some introductory information about cholesterol and eating heart healthy. Do you think you know enough about cholesterol now? Take the quiz and see how well you stack up in your cholesterol knowledge!
Comments from Participants: What you like to know about what some of our past participants thought about the study? We had each participant and his/her parent fill out an evaluation form to let us know how we did and we can improve your experience. See comments from both the kids and their parents to see what their points of view were.

Acknowledgments

This research is supported by National Institute of Health grants NR 04902, GM 15431, and DK 48831 (to Dr. Jason Morrow) and by gifts from the Valentine Foundation, and Judge and Mrs. Mana. The study is also performed in the Pediatric Clinical Research Center in the Children's Hospital at University of California, San Francisco funded by grant M01 RR-01271 and in the General Clinical Research Center, University of California, San Francisco, funded by grant M01-00079, National Center for Research Resources, USPHS.

We gratefully thank the nurses and laboratory staff in the Pediatric Clinical Research Center and the dietetic staff of the General Clinical Research Center at the University of California, San Francisco Medical Center for their exceptional assistance with this study.

We would also like to give special thanks to Great Earth Vitamins for kindly providing the antioxidant vitamin supplements, and to Martek Biosciences Corporation for providing the omega-3 fatty acids supplements during this study.

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